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Coronavirus: an overview and details study about their replication & pathogenesis

Jagrati Chaurasia , Atul Chaurasia , Vivek Gautam , A.K.Singhai

DIP: 18.02.004/20200502

DOI: 10.25215/2455/0502004

Received: April 07, 2020; Revision Received: May 12, 2020; Accepted: June 25, 2020

Abstract

Coronaviruses (CoV) belong to the genus Corona virus with its high mutation rate in the Coronaviridae. Coronaviruses (CoVs), enveloped positive-sense RNA viruses, are characterized by club-like spikes that project from their surface, an unusually large RNA genome, and a unique replication strategy. Coronaviruses cause a variety of diseases in mammals and birds ranging from enteritis in cows and pigs and upper respiratory disease chickens to potentially lethal human respiratory infections. Here we provide a brief introduction to coronaviruses discussing their replication and pathogenicity, and current prevention and treatment strategies. We will also discuss the outbreaks of the highly pathogenic Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV).as well as the medicines which are used for treatment of CoVs.

The authors profoundly appreciate all the people who have successfully contributed to ensuring this paper in place. Their contributions are acknowledged however their names cannot be mentioned.

The author declared no conflict of interest.

This is an Open Access Research distributed under the terms of the Creative Commons Attribution License (www.creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any Medium, provided the original work is properly cited.

Responding Author Information

Jagrati Chaurasia @ jagratichaurasia2@gmail.com

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Article Overview

ISSN 2348-5396

ISSN 2349-3429

DIP: 18.02.004/20200502

DOI: 10.25215/2455/0502004

Published in

Volume 05, Issue 2, April-June, 2020

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